IHPE – ANGORA Etienne english

Etienne_ ANGORAIHPE UMR 5244
University of Perpignan via Domitia
52 Avenue Paul Alduy
F-66860 Perpignan Cedex FRANCE
Tel +33(0)4-68-66-20-50
Fax +33(0)4-68-66-22-81
email : angorakpongbo2005@yahoo.fr
POSITION: PhD student (download resume)
THESIS DIRECTORS: Jérôme BOISSIER & Olivier BALMER
TEAM: ECOEVI
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THESIS TITLE:
Population genetic structure and hybridization of Schistosomes among schoolchildren in Côte d’Ivoire
KEYWORDS:
Schistosomes ; Hybrids ; Genetic diversity ; Côte d’Ivoire
THESIS SUBJECT:
Schistosomiasis remains a great public health problem in several tropical and subtropical countries. The urogenital form caused by Schistosoma haematobium, whose intermediate host is the freshwater snail Bulinus, is widespread in Africa. The disease leads to haematuria in patients. In Côte d’Ivoire, the parasitic disease prevalence in known foci ranges from 8 to 42.8%. A national mass-treatment program is in place and is implemented by the Ministry of Health following WHO guidelines. This program action allows lowering the prevalence of schistosomiasis. In an effort to eliminate the disease, epidemiological surveys are used to identify rich area for infection. With documented genetic crossing occurring between species, it is important to look for heterogeneity of an infection, which may strongly influence development of new variants of the parasite. Indeed, hybridization of S. haematobium and S. mansoni has been documented from an Ivorian patient presenting at the University Hospital of Perpignan (Jerome Boissier: personal communication). Thus, this study aims to determine the genetic diversity of S. haematobium among school-aged children and to detect S. haematobium hybridization with other schistosome species. The study will include parasitological examination of 400 children from four geographically distinct study sites to determine the S. haematobium the prevalence rate by means of urine sample filtration. Then, 30 miracidia from 30 positive urines samples will be collected onto FTA cards in order to perform genetic analyses. After genomic DNA isolation and Cox 1 and ITS 2 PCR will be used to determine schistosome hybrids. DNA will be genotyped using microsatellite markers to determine the genetic polymorphism in each study site. The results of this study will contribute to the monitoring and implementation of strategies for effective infectious disease control and development in molecular epidemiology, biology and clinical trials.
RESUME:
2018- PhD
2014  Master in Functional and Molecular Biology, Felix Houphouët-Boigny University (Abidjan, Côte d’Ivoire) & Certificate of Special Studies (CES) in Immunology, Felix Houphouët-Boigny University (Abidjan, Côte d’Ivoire)
2013 CES in Hematology-Biology, Felix Houphouët-Boigny University (Abidjan, Côte d’Ivoire) & CES in Medical and Technical Parasitology, Felix Houphouët-Boigny University (Abidjan, Côte d’Ivoire)
2012 Master in Public Health, University of Abidjan-Cocody
2008 Pharmacy Doctor Degree, University of Abidjan-Cocody
2007 Admission to the internship exam in Pharmacy
2000 High School Leaving Certificate (Mathematic and Physical sciences).
AWARDS:
May 2017: Award for Young Researcher in Parasitology, PASRES, Abidjan
December 2016: Best Poster Award, Congress of the African Society of Parasitology (SOAP), Bamako, Mali
TEACHING:
Assistant professor, Department of Parasitology-Mycology, Zoology, School of Pharmacy, Felix Houphouët-Boigny University (Abidjan, Côte d’Ivoire)
PUBLICATIONS BEFORE IHPE :
K.E. Angora, V. Djohan, A. Konaté, P. C. Kiki Barro, A. V. Bedia-Tanoh, K. Fulgence Kassi, A. He. Vanga-Bosson, Sébastien Miezan, E. Hervé Menan, and W. Yavo. Uncomplicated Malaria and Intestinal Helminth Co-Infections among Schoolchildren in Abobo District, Abidjan (Côte d’Ivoire). J Infect Dis Epidemiol 5:064.
– H. Bosson-Vanga, K. E. Angora, A. Konaté, A.V. Bédia-Tanoh, S. Miézan, P. Kiki-Barro1, K. Fulgence Kassi, V. Djohan, W. Yavo and H. Menan. Anticandidosic activity of selected medicinal plants from Côte d’Ivoire. Journal of Yeast and Fungal Research 2018, 9(4): 27-32
– H. Bosson-Vanga, A. Konate, K. E. Angora, A. Bonouman- Ira, V. Djohan, A.K. Bedia, P.C.M. Kiki-Barro, K.F. Kassi, W. Yavo, E.I.H. Menan, O.A. Touré. Profil des otomycoses diagnostiquées à l’Institut Pasteur de Côte d’Ivoire. Rev int sc méd –RISM 2018;20,3:207-212.
K. E. Angora, V. Djohan, V. A. Ira-Bonouman, H. A. Vanga-Bosson, K. F. Kassi, A. Konaté, V. A. Bedia-Tanoh, S. A. Miezan, C. P. Kiki-Barro, H.Menan , A. Offianan Touré, W. Yavo. Susceptibility of Candida spp isolated from recurrent vulvovaginal candidiasis to antifungal agents among women at Institut Pasteur of Côte d’Ivoire. Journal of Yeast and Fungal Research 2018, 9(3): 21-26
Angora KE, Ako AB, Bosson -Vanga AH, Ira-Bonouman AV, Touré OA, Menan HE, Djaman AJ. Phenol-Chloroform-based isolation of Schistosoma haematobium DNA in urine samples at Institut Pasteur of Côte d’Ivoire. African Journal of Parasitology Research 2018, 5 (11):360-365
Angora KE, Kiki-Barro PCM, Kassi KF, Konaté A, Vanga-Bosson AH, Bedia-Tanoh AV, Miezan S, Djohan V, Menan HE, Yavo W. Aetiology of intestinal parasitosis in children suffering from malnutrition in Abidjan, Côte d’Ivoire. African Journal of Parasitology Research 2018, 5 (4) : 287-295
K.E. Angora, A. Ira-Bonouman , A.H. Vanga-Bosson, A. Konaté a, F.K. Kassi, K. Tuo, K. Sylla-Thanon, P.C. Kiki-Barro, S. Miezan, A.V. Bedia-Tanoh, V. Djohan, W. Yavo, E.H. Menan, A.T. Offianan. Caractéristiques cliniques et mycologiques des onychomycoses à Candida à l’Institut Pasteur de Côte d’Ivoire. Journal de Mycologie Médicale 2018 28, 167—172
– A. Konaté, P. C. M. Barro-Kiki, K. E. Angora, A. V. Bédia-Tanoh, V. Djohan, K. F. Kassi, H. Vanga-Bosson, A. J.S. Miézan, S. B.Assi, E.I. H. Menan, W. Yavo. Efficacy and tolerability of artesunate-amodiaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria at two sentinel sites across Côte d’Ivoire Annals of Parasitology 2018, 64(1), 49–57