Delphine1IHPE UMR 5244
University of Montpellier
Place Eugène Bataillon CC 80
F-34095 Montpellier Cedex 5 FRANCE
Tel +33(0)4-67-14-46-25
Fax +33(0)4-67-14-46-22
email: ddestoum@ifremer.fr
POSITION : Researcher CNRS
– Head of the team MIMM
– Co-organizer of the  symposium AMP2016
 SCIENTIFIC SOCIAL NETWORKS  : (click on the logo)           
From 1995 to 2000, my research has focused on the role of antimicrobial peptides (AMPs) in the innate immunity of vertebrates and invertebrates. As a graduate student (Bachère lab, University of Montpellier, France) and then as a post-doctoral fellow (Ganz lab, UCLA, USA), I have characterized the structure and expression of diverse AMP families (e.g. penaeidins, b-defensins). Hired as a permanent researcher at the CNRS in 2000, I have studied the role of AMPs in microbial competitions and characterized AMP biosynthetic pathways, structures and modes of action with a particular interest in the hijacking of iron uptake systems. Since 2006, I have focused my research on the molecular interplay between hosts and microorganisms using the oyster-vibrio interaction as a model. One central question I am addressing is what makes the oyster pathogens and commensals able to circumvent their host antimicrobial response. With that goal, I am exploring oyster/vibrio interactions from their diversity to the mechanisms sustaining their infectious success (colonization and immune evasion). The role of the environment in the emergence/selection of those adaptive traits and in the transmission of vibrios to oysters is also part of my current scientific interests. Those projects are developed at different scales (molecule, cell, organism, and ecosystem) in close collaboration with colleagues from the MIMM team and diverse French and European laboratories (Frédérique le Roux, Sun Wai, Melanie Blokesch…).
– Researcher of the Future for the Languedoc Roussillon Region in 2009
2007 Habilitation Thesis (University of Paris VI)
1998 Ph.D (University of Montpellier II)
1995 Masters, Microbiology and Biotechnologies (University of Toulouse Paul Sabatier)
1995 Engineer in Biochemical and Food Engineering  (National Institute of Applied Sciences INSA, Toulouse)
– Masters degree. University of Montpellier . Molecular effectors of host-pathogen interactions. Immunity of marine invertebrates (FMOE 201 ; FMOM 301).