IHPE – MIMM english

TEAM MIMM
Mechanisms of Adaptation and Interaction in the Marine Environment
Head : Delphine DESTOUMIEUX-GARZÓN

In a context of global change, environmental stressors are increasingly affecting marine invertebrates, which are the subject of mortality outbreaks of multiple origins. Species living in marine costal habitats and lagoons are particularly affected as they are exposed to microorganisms brought by rainfalls along the catchment areas, pathogens present in the coastal environment and occasional toxic algal blooms. Moreover, in those ecosystems characterized by shallow waters, marine invertebrates have to face rapid shifts in temperature and salinity and exposure to xenobiotics of anthropogenic origin. Because of the diversity of biotic and abiotic stressors and because their impact and possible synergies on invertebrate physiology and fitness are still unknown, ecological collapses affecting marine invertebrates are still difficult to predict. In this context, we are developing integrative studies to decipher multifactoral diseases affecting Crassostrea gigas oysters, as a species of interest in aquaculture, and Pocillopora damicornis corals, as a species of ecological interest.
Our objectives are on the one hand, to describe the mechanisms that govern host-pathogen-environment interactions coming into play in marine environments, in particular during disease outbreaks, and on the other hand, to characterize the physiological and adaptive responses of invertebrates and their pathogens subjected to environmental stressors. We will study the mechanisms of interaction, their diversity and their dynamics under environmental pressure.

A postdoctoral position for 2016 (closed)
Hemomicrobiota of the oyster: microbial diversity and dynamics during experimental pathogenesis in Crassostrea gigas.  informations

MIMM sept 2015

From left to right: Agnès Vergnes, Delphine Destoumieux-Garzon, Philippe Haffner, Caroline Montagnani, Maxime Lafont, Célina Abi Khalil, Tristan Rubio, Evelyne Bachère, Jean-Luc Rolland, Aurore Poirier, Julien De Lorgeril, Yannick Gueguen, Guillaume Charrière, Jean-Michel Escoubas. (Not on the picture: Guillaume Mitta, Marc Leroy, Thierry Noel, Rodolfo Rondon, Kelly Brener Raffalli)
PERMANENT STAFF:
DESTOUMIEUX-GARZÓN Delphine Researcher CNRS (90%)
BACHÈRE Evelyne
Researcher Ifremer (100%)
CHARRIERE Guillaume
Assistant Professor University of Montpellier (100%)
DE LORGERIL Julien
Researcher Ifremer (100%)
ESCOUBAS Jean-Michel
Researcher CNRS (100%)
GUEGUEN Yannick
Researcher Ifremer (100%)
HAFFNER Philippe
Technician Ifremer (100%)
LAGORCE Arnaud
Assistant Professor University of Perpignan (100%)
- LEROY Marc
Technician CNRS (100%)
MITTA Guillaume
Professor University of Perpignan (100%)
MONTAGNANI Caroline
Researcher Ifremer (90%)
NOËL Thierry
Researcher Ifremer (10%)
ROLLAND Jean-Luc
Researcher Ifremer (100%)
VERGNES Agnès
Technician Ifremer (100%)
VIDAL-DUPIOL Jérémie
Researcher Ifremer (100%)
NON PERMANENT STAFF:
BRENER RAFFALLI Kelly, Ph.D student, University of Perpignan
LAFONT Maxime, Ph.D student, Ifremer & University of Perpignan
LUCASSON Aude, Ph.D student, University of Montpellier
OYANEDEL TRIGO Daniel, Ph.D student, University of Chili
ROBINO Etienne, Ph.D student, University of Montpellier
RUBIO Tristan, Ph.D student, University of Montpellier
DUPONT Samuel, postdoctoral fellowship, University of Montpellier
CLERISSI Camille, postdoctoral fellowship, CNRS (50% MIMM, 50% ECOEVI)
 FORMER COLLABORATORS …
ABI KHALIL Celina, Ph.D student, University of Montpellier
- POIRIER Aurore (Ph.D student 2012-2015) Postdoctoral Fellow, Institute for Liver & Digestive Health, University College, London, UK @
RONDON Rodolfo (Ph.D student 2013-2015)
LOPEZ-JOVEN Carmen (Postdoctoral Fellow 2013-2015) Postdoctoral Fellow, Universidad Austral de Chile, Valdivia, Chili   email
VANHOVE Audrey (Ph.D student 2011-2014) Postdoctoral Fellow, Boston Children’s Hospital/Harvard Medical School, MI, USA    email
 - GREEN Tim (Post Ph.D 2012-2013) Postdoctoral Fellow, University of Macqurie, Marine and Freshwater Biology Laboratory (David Raftos) Sydney, Australia  email
VIDAL-DUPIOL Jérémie (doctorant 2007-2011) Researcher IRD, Tahiti, French Polynesia email
ROSA Rafael (Ph.D student 2008-2011) Professor, Laboratory of Immunology Applied to Aquaculture, Department of Cell Biology, Embryology and Genetics, Federal University of Santa Catarina, 88040-900 Florianópolis, SC, Brazil
DUPERTHY Marylise (Ph.D student 2007-2010) Postdoctoral Fellow, Department of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, 901 87 Umeå, Sweden  email  
SCHMITT Paulina (Ph.D student 2007-2010) Researcher, Laboratory « Genética e Inmunología Molecular, Instituto de Biología, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso », Av. Brasil 2950, Valparaíso, Chili  email
GONZALEZ Marcelo (Ph.D student 2002-2005) Researcher, INACH « Instituto Antartico Chileno »  – Laboratorio de Biorrecursos Antárticos – Punta Arenas Chili

NATIONAL COLLABORATIONS:
- Frédérique LE ROUX, Ifremer, PFOM, Roscoff Biological Station
– Agnès TRAVERS, Ifremer, La Tremblade
– Bruno PETTON & Pierre BOUDRY, Ifremer, PFOM, Brest
– Annick JACQ, University of Orsay
– Claudine MEDIGUE, Génoscope, Ivry
– Farida AKCHA, Ifremer, Laboratory of Ecotoxicology, Nantes
– David PIQUEMAL, ACOBIOM, Montpellier
– Alain GIVAUDAN & Sophie GAUDRIAULT, INRA, Montpellier
– Hervé COTTET, Institut Max Mousseron, Montpellier  
INTERNATIONAL COLLABORATIONS:
- Sun NYUNT WAI & Marylise DUPERTHUY, The laboratory for molecular infection and medicine, University of Umea, Sweden
– Mélanie BLOKESCH & Charles VAN DER HENST, Ecole Polytechnique Fédérale of Lausanne (EPFL), Switzerland
– Hans-Georg SAHL, University of Bonn, Germany
- Rafael DA ROSA, University of Florianopolis, Brazil
– Marcelo GONZALEZ, Institut Antarctique Chilien (INACH), Chili
– Timothy GREEN, Macquarie University, Australia
– Paulina SCHMITT, Pontificia Universidad Católica de Valparaiso, Chili

VIBRIOGEN (2011-2016) – ANR -
Les vibrios pathogènes d’invertébrés marins: un nouveau regard sur la virulence et les réservoirs de gènes permettant l’adaptation à la niche écologique
DECIPHER (2014-2019) – ANR –
Déchiffrage des maladies multifactorielles : cas des mortalités de l’huître
ADACNI (2012-2016) – ANR –
Processus adaptatifs chez les cnidaires / Etude intégrative de la réponse au stress thermique et au changement climatique des gênes aux populations
- GIMEPEC (2012-2015) – ANR -
Génotoxicité, immunotoxicité et reprotoxicité des pesticides chez Crassostrea gigas
- InterVibrio (2014-2015) – Ec2co/INSU + crédits d’incitation Ifremer
Rôle du plancton dans la transmission des vibrios pathogènes aux huîtres
- PROVIGAS (2014-2017) – Région Languedoc Roussillon -
PROtection antiVIrale de l’huître Crassostrea giGAS

PREVIOUS GRANTS

- APOTOX (2013-2014) – Ec2co/INSU -
Etude des effets apoptotiques induits par les neurotoxines du dinoflagellé Alexandrium catenella chez l’huître Crassostrea gigas : conséquences sur la susceptibilité des huîtres aux pathogènes
 - BigDef (2013-2014) -
Vaincre la Mucoviscidose – Activité des défensines et big défensines d’invertébrés marins contre les pathogènes majeurs impliqués dans la mucoviscidose
- AESTU+ (2014) – DPMA -
Mortalités d’huîtres creuses adultes (Crassostrea gigas) et infection à Vibrio aestuarianus – suite
- SIGNAGENE2 (2014) – Région Languedoc Roussillon -
Utilisation de biomarqueurs génétiques en soutien à la sélection de souches d’huîtres présentant de meilleures capacités de survie
- GENEPIH (2014) – eC2CO/INSU -
Modifications génétiques et épigénétiques d’une exposition au diuron chez l’huître creuse
 - Pathogas (2013-2014) – Crédit incitation Ifremer -
Peptides antimicrobiens, microbiome et homésotasie chez l’huitre C. gigas