IHPE – MONE Helene english

HeleneIHPE UMR 5244
University of Perpignan via Domitia
52 Avenue Paul Alduy
F-66860 Perpignan Cedex FRANCE
Tel +33(0)4-68-66-21-84
Fax +33(0)4-68-66-22-81
email: mone@univ-perp.fr
POSITION : Researcher CNRS
TEAM : ECOEVI
 SCIENTIFIC SOCIAL NETWORKS:
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RESEARCH – EXPERTISE AREA :
Evolutionary ecology and epidemiology of the systems host-parasite:
There was, in broad outline, during my career, two periods. The first one, up to the early 2000s, consisted of the study of the ecology of the interactions host-parasite and interactions host-parasite-environnement and in the study of the evolutionary relations in the systems host-parasite by using an essentially experimental approach and a privileged model, the schistosome, helminthe parasite of the Man.
During the second period (2000 – present), I wished to have a wider vision of these interactions, integrating evolutionary ecology and epidemiology, by using an approach integrated by the understanding of the functioning of the homes of transmission of parasitoses, allying epidemiological studies of ground and experiments in laboratory. So, to the model nématode parasite of the eel, I analyzed the epidemiology, the biology and the ecophysiology of the relations host-parasite. Concerning the model of schistosomes, I analyzed the interactions sex dependent during the biological cycle and the functioning of the homes  of transmission in zones of  weakness (Oman) and strong (Benin, Gabon) endemic diseases.
Evolutionary ecology and epidemiology to schistosomes: impact of the polyparasitisme on the parasitic diversity My project concerns the evolutionary ecology and the epidemiology of the sustainable interactions to schistosomes.
I suggest analyzing the impact of the polyparasitisme on the parasitic diversity. I shall be interested in the polyparasitisme inter-populations to understand the role of the hosts reservoirs in the re-emergence of schistosomoses, in the polyparasitisme inter-species to detect events of introgressives hybridizations in strongly endemic zones of the schistosomose and in the polyparasitisme inter-genres (Schistosoma and Plasmodium) to analyze the quantitative and qualitative impacts of schistosomes on the paludal infection and, on the contrary, the impact of Plasmodium on the genetic variability and the antigenic polymorphism of schistosomes. I realize my research according to an approach integrated by the understanding of the functioning of the homes of transmission of parasitoses, by allying epidemiological studies of ground and analyses in laboratory. The results have practical implications on the structure of the communities of parasites and hosts and can be used for purposes of control of schistosomoses
 RESUME :
1993 – Habilitation Thesis (University of Perpignan, France)
1984 – Ph.D Parasitology (University of  Montpellier II, France)
1981 – Degree of initiation to research Parasitology (University of Montpellier II, France)
TEACHING :
– Master (University of Perpignan)
– Trainers’ training(formation) and in-service training of health workers
– Participation to many acts of scientific culture diffusion
PUBLICATIONS in the lab with impact factor:link
PUBLICATIONS out of the lab without impact factor:
– Mintsa NGuema R., Mavoungou J.F., Mengue Me Ngou-Milama K., Mabicka Mamfoumbi M., Koumba A.A., Sani Lamine M., Diarra A., Nkone Asseko G., Mourou J.R., Bouyou Akotet M.K., Moné H., Mouahid G. and Atsame J. (2018) Baseline mapping of schistosomiasis and soil transmitted helminthiasis in the northern and eastern health regions of Gabon, Central Africa: recommendations for preventive chemotherapy. Tropical Medicine and Infectious Diseases 3: 119
– Mouahid G., Rognon A., de Carvalho Augusto R., Driguez P., Geyer K., Karinshak S., Luviano N., Mann V., Quack T., Rawlinson K., Wendt G., Grunau C. and Moné H. (2018) Transplantation of schistosome sporocysts between host snails: A video guide. Wellcome Open Research 3