IHPE – TEANINIURAITEMOANA Vaihiti english *
ACTUAL POSITION: Researcher Ifremer UMR 241 UPF-IRD-IFREMERILM Ecosysteme Insulaire Océanien – Tahiti
POSITION IN THE LAB: Post-doctoral fellowship Ifremer
SUPERVISORS: Jérémie VIDAL-DUPIOL, Serge PLANES, Céline REISSER & Chin-Long KY
SCIENTIFIC SOCIAL NETWORKS:
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SexDet project « Study of genetic and epigenetic determinism of sex change in the pearl oyster P. margaritifera »
Genomics ; Next-Generation-Sequencing ; Reproduction ; Sex determinism and sex differentiation
In the animal kingdom, sex can be driven by genetic factors (at fertilization), by environmental factors (during embryonic development), or can also result from an interaction between these two types of factors (mixed) through especially epigenetic modifications. Thus in most cases, sex is determined at early stage and remains fixed as in the most gonochoric species (having a separate sex). However in hermaphrodite species (which may have both sexes during their lifetime), sex changes may occur later in adults. Today, the mechanisms involved in these sex changes are still poorly known, which makes the pearl oyster Pinctada margaritifera, a protandrous hermaphrodite, a relevant model to study these mechanisms. In P. margaritifera, recent previous works strongly suggest a mixed sex determinism with, in a first degree, a genetic control determining the « True males » (do not change sex) from the « Hermaphrodites » (can change sex); and in a second degree, an epigenetic control regulating sexual inversions in « Hermaphrodites » under the influence of the environment. Thus, the objectives of this project are 1) to identify the genetic sex determinants in P. margaritifera by a Genome-Wide association study (GWAS), and 2) to characterize the epigenetic modifications involved in the regulation of sex change in P. margaritifera and in particular through a global study of genome DNA methylation (BS-Seq). This study will allow us to understand the sex determination in a protandrous hermaphrodite by combining two different approaches genetic and epigenetic and taking advantage of the new Next-Generation-Sequencing technologies.
2016-2018 Post-doctoral research fellow in genetic and epigenetic (Ifremer, UMR 241 EIO, Tahiti, French Polynesia). Research project: « Study of the genetic and epigenetic sex change determinism in the pearl oyster Pinctada margaritifera »
2015-2016 Post-doctoral research fellow in transcriptomic (IRD, UMR 9220 ENTROPIE, Nouméa, New-Caledonia). Research project: « Transcriptional response of coralline algae to predicted temperature and pH changes for 2100 »
2011-2014 Ph.D. in Biology of population and Ecology speciality Genomics of marine organisms (University of French Polynesia, Tahiti, French Polynesia). Research project: « Reproduction of the pearl oyster Pinctada margaritifera : Study of the female sex determinants in adult » (Ifremer, UMR 241 EIO, Tahiti, French Polynesia)
2010-2011 M.Sc.2 in Ecology specialty « Functioning and Dysfunction of aquatic ecosystems » (University Bordeaux I, Bordeaux, France). Research internship: « Recovery of Xenopus laevis after cadmium and zinc contamination: biochemical and genetic responses » (EA, UMR CNRS 5805 EPOC, Arcachon, France)
2009-2010 M.Sc.1 in Ecology specialty « Biological oceanology » (University Bordeaux I, Bordeaux, France). Research internship: « Interest of the cellular cytotoxicity test for the detection of ciguatera toxins in seafood » (ILM, UMR 241 EIO, Tahiti, French Polynesia)
2006-2009 B.Sc. in Life sciences specialty « Cellular biology and physiology » (University of Strasbourg, Strasbourg, France).
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