IHPE – DESTOUMIEUX-GARZON Delphine

IHPE UMR 5244
Université de Montpellier
Place Eugène Bataillon CC 80
F-34095 Montpellier Cedex 5
Tel +33(0)4-67-14-46-25
Fax +33(0)4-67-14-46-22
email: delphine.destoumieux.garzon@ifremer.fr

GRADE : Directrice de Recherche 2 CNRS (HDR)
ENCADREMENT DE THESE :
DE SAN NICOLAS Noémie
RESPONSABILITES :
– Directrice d’Unité Adjointe
– Chargée de mission CNRS INEE Eco-Health / One Health – Alliances Avisan/AllEnvi
–  Vice-Présidente de la Gordon Research Conference (2021)
–  Présidente de la Gordon Research Conference (2013)
– Co-organisatrice du symposium international AMP2016
EQUIPE : TREV

RESEAUX SOCIAUX SCIENTIFIQUES :
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DOMAINE D’EXPERTISE-RECHERCHE :
Je suis directrice adjointe du laboratoire « Interactions Hôtes-Pathogènes-Environnements ». Notre laboratoire s’intéresse aux mécanismes, à l’évolution et à la dynamique des écosystèmes conduisant à l’apparition d’agents infectieux, à leur dissémination et à leur extinction dans les habitats naturels et les hôtes.

Mes recherches personnelles portent sur les multiples facteurs des hôtes et des pathogènes contribuant à l’émergence de maladies infectieuses dans les milieux marins soumis à des changements environnementaux. Au cours de ma carrière, j’ai étudié l’immunité des invertébrés marins (crustacés et mollusques) et les maladies qui les affectent. J’ai notamment étudié les interactions entre les Vibrionaceae et le système immunitaire des bivalves marins sous contrainte environnementale.

J’ai présidé des conférences internationales sur les peptides antimicrobiens (AMP2016), la prochaine conférence Gordon sur les peptides antimicrobiens (2023) et organisé des conférences nationales sur l’immunité des invertébrés (Immuninv).

Depuis 2017, je suis chargée de mission pour le CNRS en charge de la Recherche au nexus Santé x Environnement (cadre One Health / EcoHealth).

Mes projets actuels portent sur (i) l’adaptation des Vibrio à l’huître en tant qu’hôte, y compris sur la base de leur résistance aux antimicrobiens ; (ii) les cancers transmissibles chez les moules ; (iii) la résistance aux antimicrobiens dans les milieux marins utilisés pour l’ostréiculture.

DISTINCTIONS :
2009 Chercheuse d’avenir (région Languedoc Roussillon)
2023 Vice-Présidente de la Gordon Research Conference
2025 Présidente de la Gordon Research Conference

CURSUS :
2007 Habilitation à Diriger les Recherches HDR (Université de Paris VI)
1998 Doctorat (Université de Montpellier II)
1995 DEA en Microbiologie et Biotechnologies (Université Paul Sabatier Toulouse)
1995 Ingénieur  en Génie Biochimique et Alimentaire, Génétique Microbienne (INSA Toulouse)

ENSEIGNEMENT :
– Master Interactions Microorganismes-Hôtes-Environnements. Université de Montpellier. UE HAA923V
– Master International Biologie Fonctionnelle & Ecologie. Tulip graduate school of research

PUBLICATIONS :


128 documents

Articles dans une revue61 documents

  • Eduardo Jeria, Daniel Oyanedel, Rodrigo Rojas, Rodolfo Farlora, German Lira, et al.. Resistance of Argopecten purpuratus scallop larvae to vibriosis is associated with the front-loading of immune genes and enhanced antimicrobial response. Frontiers in Immunology, 2023, 14, pp.1150280. ⟨10.3389/fimmu.2023.1150280⟩. ⟨hal-04037657⟩
  • Aurélie Mesnil, Maude Jacquot, Céline Garcia, Delphine Tourbiez, Lydie Canier, et al.. Emergence and clonal expansion of Vibrio aestuarianus lineages pathogenic for oystersin Europe. Molecular Ecology, In press, ⟨10.1111/mec.16910⟩. ⟨hal-04013412⟩
  • Noémie de San Nicolas, Aromal Asokan, Rafael Rosa, Sébastien Voisin, Marie-Agnès Travers, et al.. Functional Diversification of Oyster Big Defensins Generates Antimicrobial Specificity and Synergy against Members of the Microbiota. Marine drugs, 2022, 20 (12), pp.745. ⟨10.3390/md20120745⟩. ⟨hal-03876842⟩
  • Delphine Destoumieux-Garzón, Franziska Matthies-Wiesler, Nicolas Bierne, Aurélie Binot, Jérôme Boissier, et al.. Getting out of crises: Environmental, social-ecological and evolutionary research is needed to avoid future risks of pandemics. Environment International, 2022, 158, 12 p. ⟨10.1016/j.envint.2021.106915⟩. ⟨hal-03428100⟩
  • Maurine Hammel, Alexis Simon, Christine Arbiol, Antonio Villalba, Erika A.V. Burioli, et al.. Prevalence and polymorphism of a mussel transmissible cancer in Europe. Molecular Ecology, 2022, 31 (3), pp.736-751. ⟨10.1111/mec.16052⟩. ⟨hal-03335752⟩
  • Antoine Dujon, Joel S Brown, Delphine Destoumieux-Garzon, Marion Vittecoq, Rodrigo Hamede, et al.. On the need for integrating cancer into the One Health perspective. Evolutionary Applications, 2021, ⟨10.1111/eva.13303⟩. ⟨hal-03372780⟩
  • Robert Barouki, Manolis Kogevinas, Karine Audouze, Kristine Belesova, Ake Bergman, et al.. The COVID-19 pandemic and global environmental change: Emerging research needs. Environment International, 2021, 146, pp.106272. ⟨10.1016/j.envint.2020.106272⟩. ⟨hal-03035125⟩
  • Bruno Petton, Delphine Destoumieux-Garzόn, Fabrice Pernet, Eve Toulza, Julien de Lorgeril, et al.. The Pacific Oyster Mortality Syndrome, a polymicrobial and multifactorial disease: state of knowledge and future directions. Frontiers in Immunology, 2021, 12, pp.630343. ⟨10.3389/fimmu.2021.630343⟩. ⟨hal-03128446⟩
  • D. Destoumieux-Garzon, Pascal Bonnet, C. Teplitsky, F. Criscuolo, Pierre-Yves Henry, et al.. Animal board invited review: OneARK: Strengthening the links between animal production science and animal ecology. Animal, 2021, 15 (1), pp.100053. ⟨10.1016/j.animal.2020.100053⟩. ⟨hal-03100927⟩
  • Florie Desriac, Abderrafek El Harras, Matthieu Simon, Arnaud Bondon, Benjamin Brillet, et al.. Alterins Produced by Oyster-Associated Pseudoalteromonas are Antibacterial Cyclolipopeptides with LPS-Binding Activity. Marine drugs, 2020, 18 (12), ⟨10.3390/md18120630⟩. ⟨hal-03053494⟩
  • Jean Delmotte, Cristian Chaparro, Richard Galinier, Julien de Lorgeril, Bruno Petton, et al.. Contribution of Viral Genomic Diversity to Oyster Susceptibility in the Pacific Oyster Mortality Syndrome. Frontiers in Microbiology, 2020, 11, pp.1579. ⟨10.3389/fmicb.2020.01579⟩. ⟨hal-02915023⟩
  • Marco Gerdol, Paulina Schmitt, Paola Venier, Gustavo Rocha, Rafael Rosa, et al.. Functional insights from the evolutionary diversification of big defensins. Frontiers in Immunology, 2020, ⟨10.3389/fimmu.2020.00758⟩. ⟨hal-02545438⟩
  • Daniel Oyanedel, Yannick Labreuche, Maxime Bruto, Hajar Amraoui, Etienne Robino, et al.. Vibrio splendidus O-antigen structure: A trade-off between virulence to oysters and resistance to grazers. Environmental Microbiology, 2020, 22, pp.4264 - 4278. ⟨10.1111/1462-2920.14996⟩. ⟨hal-02996139⟩
  • Maxime Lafont, Agnès Vergnes, Jeremie Vidal-Dupiol, Julien de Lorgeril, Yannick Guéguen, et al.. A Sustained Immune Response Supports Long-Term Antiviral Immune Priming in the Pacific Oyster, Crassostrea gigas. mBio, 2020, ⟨10.1128/mBio.02777-19⟩. ⟨hal-02527469⟩
  • Craig Baker‐austin, Carla Pruzzo, James D Oliver, Delphine Destoumieux‐garzón. Vibrios – from genes to ecosystems. Environmental Microbiology, 2020, Vibrios – from genes to ecosystems, 22 (10), pp.4093 - 4095. ⟨10.1111/1462-2920.15229⟩. ⟨hal-03057595⟩
  • Delphine Destoumieux-Garzón, Laura Canesi, Daniel Oyanedel, Marie-Agnès Travers, Guillaume M Charrière, et al.. Vibrio-bivalve interactions in health and disease. Environmental Microbiology, 2020, Vibrios – from genes to ecosystems, 22 (10), pp.4323-4341. ⟨10.1111/1462-2920.15055⟩. ⟨hal-02915050⟩
  • Karine Loth, Agnès Vergnes, Cairé Barreto, Sébastien N Voisin, Hervé Meudal, et al.. The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets. mBio, 2019, 10 (5), pii: e01821-19. ⟨10.1128/mBio.01821-19⟩. ⟨hal-02328576⟩
  • Etienne Robino, Aurore Poirier, Hajar Amraoui, Sandra Le Bissonnais, Angélique Perret, et al.. Resistance of the oyster pathogen Vibrio tasmaniensis LGP32 against grazing by Vannella sp. marine amoeba involves Vsm and CopA virulence factors. Environmental Microbiology, 2019, 22, pp.4183 - 4197. ⟨10.1111/1462-2920.14770⟩. ⟨hal-02388995⟩
  • Tristan Rubio, Daniel Oyanedel, Yannick Labreuche, Eve Toulza, Xing Luo, et al.. Species-specific mechanisms of cytotoxicity toward immune cells determine the successful outcome of Vibrio infections. Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (28), pp.14238-14247. ⟨10.1073/pnas.1905747116⟩. ⟨hal-02163271⟩
  • an Ngoc Nguyen, Elena Disconzi, Guillaume Charrière, Delphine Destoumieux-Garzón, Philippe Bouloc, et al.. csrB Gene Duplication Drives the Evolution of Redundant Regulatory Pathways Controlling Expression of the Major Toxic Secreted Metalloproteases in Vibrio tasmaniensis LGP32. MSphere, 2018, 3 (6), pp.e00582-18. ⟨10.1128/mSphere.00582-18⟩. ⟨hal-01945281⟩
  • Carmen Lopez-Joven, Jean-Luc Rolland, Philippe Haffner, Audrey Caro, Cécile Roques, et al.. Oyster Farming, Temperature, and Plankton Influence the Dynamics of Pathogenic Vibrios in the Thau Lagoon. Frontiers in Microbiology, 2018, 9, pp.2530. ⟨10.3389/fmicb.2018.02530⟩. ⟨hal-01946474⟩
  • Gabriel Machado Matos, Paulina Schmitt, Cairé Barreto, Natanael Farias, Guilherme Toledo-Silva, et al.. Massive Gene Expansion and Sequence Diversification Is Associated with Diverse Tissue Distribution, Regulation and Antimicrobial Properties of Anti-Lipopolysaccharide Factors in Shrimp. Marine drugs, 2018, 16 (10), pp.381. ⟨10.3390/md16100381⟩. ⟨hal-01945121⟩
  • Julien de Lorgeril, Jean-Michel Escoubas, Vincent Loubiere, Fabrice Pernet, Patrik Le Gall, et al.. Inefficient immune response is associated with microbial permissiveness in juvenile oysters affected by mass mortalities on field. Fish and Shellfish Immunology, 2018, 77, pp.156 - 163. ⟨10.1016/j.fsi.2018.03.027⟩. ⟨hal-01759229⟩
  • Delphine Destoumieux-Garzón, Patrick Mavingui, Gilles Boëtsch, Jérôme Boissier, Frédéric Darriet, et al.. The One health concept : 10 years old and a long road ahead. Frontiers in Veterinary Science, 2018, 5, pp.14. ⟨10.3389/fvets.2018.00014⟩. ⟨hal-01722566⟩
  • Julien de Lorgeril, Aude Lucasson, Bruno Petton, Eve Toulza, Caroline Montagnani, et al.. Immune-suppression by OsHV-1 viral infection causes fatal bacteraemia in Pacific oysters. Nature Communications, 2018, 9 (1), pp.4215. ⟨10.1038/s41467-018-06659-3⟩. ⟨hal-01898110⟩
  • Celina Abi-Khalil, Darren S. Finkelstein, Geneviève Conejero, Justin Du Bois, Delphine Destoumieux-Garzon, et al.. The paralytic shellfish toxin, saxitoxin, enters the cytoplasm and induces apoptosis of oyster immune cells through a caspase-dependent pathway. Aquatic Toxicology, 2017, 190, ⟨10.1016/j.aquatox.2017.07.001⟩. ⟨hal-01561503⟩
  • Delphine Destoumieux-Garzón, R. D. Rosa, P. Schmitt, C. Barreto, Jeremie Vidal-Dupiol, et al.. Antimicrobial peptides in marine invertebrate health and disease. Philosophical Transactions of the Royal Society B: Biological Sciences, 2016, 371 (1695), pii: 20150300. ⟨10.1098/rstb.2015.0300⟩. ⟨hal-01316402⟩
  • A.S. Vanhove, T.P. Rubio, A.N. Nguyen, A. Lemire, D. Roche, et al.. Copper homeostasis at the host vibrio interface: lessons from intracellular vibrio transcriptomics. Environmental Microbiology, 2016, Pathogen Ecology, 18 (3), pp.875-888. ⟨10.1111/1462-2920.13083⟩. ⟨hal-01311061⟩
  • Paulina Schmitt, Rafael Diego Rosa, Delphine Destoumieux-Garzón. An intimate link between antimicrobial peptide sequence diversity and binding to essential components of bacterial membranes. Biochimica et Biophysica Acta:Biomembranes, 2016, 1858 (5), pp.958-970. ⟨10.1016/j.bbamem.2015.10.011⟩. ⟨hal-01311099⟩
  • Denis Faure, Patricia Bonin, Robert Duran, Pierre Amato, Florence Arsene-Ploetze, et al.. Environmental microbiology as a mosaic of explored ecosystems and issues. Environmental Science and Pollution Research, 2015, 22 (18), pp.13577-13598. ⟨10.1007/s11356-015-5164-5⟩. ⟨hal-01247096⟩
  • Frédérique Le Roux, K Mathias Wegner, Craig Baker-Austin, Luigi Vezzulli, Carlos R Osorio, et al.. The emergence of Vibrio pathogens in Europe: ecology, evolution, and pathogenesis (Paris, 11-12th March 2015).. Frontiers in Microbiology, 2015, 6, pp.830. ⟨10.3389/fmicb.2015.00830⟩. ⟨hal-01464526⟩
  • Evelyne Bachère, Rafael Diego Rosa, Paulina Schmitt, Aurore Poirier, Nicolas Merou, et al.. The new insights into the oyster antimicrobial defense: cellular, molecular and genetic view. Fish and Shellfish Immunology, 2015, 46 (1), pp.50-64. ⟨10.1016/j.fsi.2015.02.040⟩. ⟨hal-01162911⟩
  • Audrey Sophie Vanhove, Marylise Duperthuy, Guillaume M Charrière, Frédérique Le Roux, David Goudenège, et al.. Outer membrane vesicles are vehicles for the delivery of Vibrio tasmaniensis virulence factors to oyster immune cells.. Environmental Microbiology, 2015, Pathogen ecology and lifestyles, 17 (4), pp.1152-1165. ⟨10.1111/1462-2920.12535⟩. ⟨halsde-01054322⟩
  • Vanessa W Petit, Jean-Luc Rolland, Alain Blond, Chantal Cazevieille, Chakib Djediat, et al.. A hemocyanin-derived antimicrobial peptide from the penaeid shrimp adopts an alpha-helical structure that specifically permeabilizes fungal membranes. Biochimica et Biophysica Acta (BBA) - General Subjects, 2015, 1860 (3), pp.557-568. ⟨10.1016/j.bbagen.2015.12.010⟩. ⟨hal-01259500⟩
  • Nicolas Sisavath, Patrice Got, Guillaume Charrière, Delphine Destoumieux-Garzón, Hervé Cottet. Taking advantage of electric field induced bacterial aggregation for the study of interactions between bacteria and macromolecules by capillary electrophoresis. Analytical Chemistry, 2015, 87 (13), pp.6761-6768. ⟨10.1021/acs.analchem.5b00934⟩. ⟨hal-01259864⟩
  • Aurore Poirier, Paulina Schmitt, Rafael Rosa, Audrey Vanhove, Sylvie Kieffer-Jaquinod, et al.. Antimicrobial Histones and DNA Traps in Invertebrate Immunity. Journal of Biological Chemistry, 2014, 289 (36), pp.24821-24831. ⟨10.1074/jbc.M114.576546⟩. ⟨hal-02086276⟩
  • Farid Oukacine, Joselito P. Quirino, Delphine Destoumieux-Garzón, Hervé Cottet. Field enhanced bacterial sample stacking in isotachophoresis using wide-bore capillaries. Journal of Chromatography A, 2012, 1268, pp.180-184. ⟨10.1016/j.chroma.2012.10.026⟩. ⟨hal-00778576⟩
  • Bernard Duvic, Véronique Jouan, Nour Essa, Pierre-Alain Girard, Sylvie Pages, et al.. Cecropins as a marker of Spodoptera frugiperda immunosuppression during entomopathogenic bacterial challenge. Journal of Insect Physiology, 2012, 58 (6), pp.881 - 888. ⟨10.1016/j.jinsphys.2012.04.001⟩. ⟨hal-02651570⟩
  • Jeremie Vidal-Dupiol, Ophélie Ladrière, Delphine Destoumieux-Garzón, Pierre-Eric Sautière, Anne-Leila Meistertzheim, et al.. Innate immune responses of a scleractinian coral to vibriosis.. Journal of Biological Chemistry, 2011, 286 (25), pp.22688-98. ⟨10.1074/jbc.M110.216358⟩. ⟨halsde-00608446⟩
  • Marylise Duperthuy, Johan Binesse, Frédérique Le Roux, Bernard Romestand, Audrey Caro, et al.. The major outer membrane protein OmpU of Vibrio splendidus contributes to host antimicrobial peptide resistance and is required for virulence in the oyster Crassostrea gigas. Environmental Microbiology, 2010, 12 (4), pp.951-963. ⟨10.1111/j.1462-2920.2009.02138.x⟩. ⟨hal-02667966⟩
  • Delphine Destoumieux-Garzón, Michel Brehélin, Philippe Bulet, Yvan Boublik, Pierre-Alain Girard, et al.. Spodoptera frugiperda X-tox protein, an immune related defensin rosary, has lost the function ancestral defensins. PLoS ONE, 2009, 4 (8), pp.e6795. ⟨10.1371/journal.pone.0006795⟩. ⟨hal-02665408⟩
  • Yinshan Yang, Hélène Boze, Patrick Chemardin, André Padilla, Guy Moulin, et al.. NMR structure of rALF-Pm3, an anti-lipopolysaccharide factor from shrimp: Model of the possible lipid A-binding site.. Biopolymers, 2009, 91 (3), pp.207-20. ⟨10.1002/bip.21119⟩. ⟨hal-03726710⟩
  • Yinshan Yang, Hélène Boze, Patrick Chemardin, André Padilla, Guy Moulin, et al.. NMR structure of rALF-Pm3, an anti-lipopolysaccharide factor from shrimp: Model of the possible lipid A-binding site.. Biopolymers, 2009, 91 (3), pp.207-20. ⟨10.1002/bip.21119⟩. ⟨hal-00358510⟩
  • Ziad Abi-Khattar, Agnes A. Rejasse, D. Destoumieux-Garzon, Jean-Michel Escoubas, Vincent V. Sanchis Borja, et al.. The dlt Operon of Bacillus cereus Is Required for Resistance to Cationic Antimicrobial Peptides and for Virulence in Insects. Journal of Bacteriology, 2009, 191 (22), pp.7063-7073. ⟨10.1128/JB.00892-09⟩. ⟨hal-02664630⟩
  • G. Vassiliadis, J. Peduzzi, D. Destoumieux-Garzón, S. Zirah, X. Thomas, et al.. Biosynthesis of siderophore-peptides, a class of potent antimicrobial peptides from enterobacteria, requires two precursors.. Advances in Experimental Medicine and Biology, 2009, 611, pp.33-4. ⟨hal-00393740⟩
  • Sophie Duquesne, Delphine Destoumieux-Garzón, Séverine Zirah, Thomas A Knappe, Christophe Goulard, et al.. Post-translational modification and folding of a lasso-type gene-encoded antimicrobial peptide require two enzymes only in Escherichia coli.. Advances in Experimental Medicine and Biology, 2009, 611, pp.35-6. ⟨hal-00393753⟩
  • Marcelo Gonzalez, Yannick Gueguen, Delphine Destoumieux-Garzón, Bernard Romestand, Julie Fievet, et al.. Evidence of a bactericidal permeability increasing protein in an invertebrate, the Crassostrea gigas Cg-BPI. Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (45), pp.17759-64. ⟨10.1073/pnas.0702281104⟩. ⟨hal-00258926⟩
  • S. Duquesne, D. Destoumieux-Garzón, J. Peduzzi, S. Rebuffat. Microcins, gene-encoded antibacterial peptides from enterobacteria.. Natural Product Reports, 2007, 24 (4), pp.708-734. ⟨10.1039/b516237h⟩. ⟨hal-00146730⟩
  • Gaëlle Vassiliadis, Jean Peduzzi, Séverine Zirah, Xavier Thomas, Sylvie Rebuffat, et al.. Insight into siderophore-carrying peptide biosynthesis: Enterobactin is a precursor for microcin E492 post-translational modification.. Antimicrobial Agents and Chemotherapy, 2007, 51 (10), epub ahead of print. ⟨10.1128/AAC.00261-07⟩. ⟨hal-00167749⟩
  • S. Duquesne, D. Destoumieux-Garzón, S. Zirah, C. Goulard, J. Peduzzi, et al.. Two Enzymes Catalyze the Maturation of a Lasso Peptide in Escherichia coli. Chemistry & Biology / Chemistry and Biology; CHEMISTRY & BIOLOGY, 2007, 14 (7), pp.793-803. ⟨10.1016/j.chembiol.2007.06.004⟩. ⟨hal-00152101⟩
  • Mathieu Pernice, D. Destoumieux-Garzon, Jean Peduzzi, Sylvie Rebuffat, Renata Boucher-Rodoni. Identification of a Vibrio strain producing antimicrobial activities in the excretory organs of Nautilus pompilius (Cephalopoda, Nautiloidea).. Reviews in Fish Biology and Fisheries, 2007, 17, pp.197-205. ⟨10.1007/s11160-006-9029-3⟩. ⟨hal-00146199⟩
  • M. Pernice, D. Destoumieux-Garzón, J. Peduzzi, S. Rebuffat, R. Boucher-Rodoni. Identification of a Vibrio strain producing antimicrobial agents in the excretory organs of Nautilus pompilius (Cephalopoda, Nautiloidea).. Rev Fish Biol Fisheries, 2007, 17 (2-3), pp.197-205. ⟨10.1007/s11160-006-9029-3⟩. ⟨hal-00145822⟩
  • Delphine Destoumieux-Garzón, Jean Peduzzi, Xavier Thomas, Chakib Djediat, Sylvie Rebuffat. Parasitism of iron-siderophore receptors of Escherichia coli by the siderophore-peptide microcin E492m and its unmodified counterpart.. BioMetals, 2006, 19 (2), pp.181-91. ⟨10.1007/s10534-005-4452-9⟩. ⟨hal-00129149⟩
  • Delphine Destoumieux-Garzón, Sophie Duquesne, Jean Peduzzi, Christophe Goulard, Michel Desmadril, et al.. The iron-siderophore transporter FhuA is the receptor for the antimicrobial peptide microcin J25: role of the microcin Val11-Pro16 beta-hairpin region in the recognition mechanism.. Biochemical Journal, 2005, 389 (Pt 3), pp.869-76. ⟨10.1042/BJ20042107⟩. ⟨hal-00130139⟩
  • Sylvie Rebuffat, Alain Blond, Delphine Destoumieux-Garzón, Christophe Goulard, Jean Peduzzi. Microcin J25, from the macrocyclic to the lasso structure: implications for biosynthetic, evolutionary and biotechnological perspectives.. Current Protein and Peptide Science, 2004, 5 (5), pp.383-91. ⟨hal-00016002⟩
  • Xavier Thomas, Delphine Destoumieux-Garzón, Jean Peduzzi, Carlos Afonso, Alain Blond, et al.. Siderophore peptide, a new type of post-translationally modified antibacterial peptide with potent activity.. Journal of Biological Chemistry, 2004, 279 (27), pp.28233-42. ⟨10.1074/jbc.M400228200⟩. ⟨hal-00016010⟩
  • Delphine Destoumieux-Garzón, Xavier Thomas, Mónica Santamaria, Christophe Goulard, Michel Barthélémy, et al.. Microcin E492 antibacterial activity: evidence for a TonB-dependent inner membrane permeabilization on Escherichia coli.. Molecular Microbiology, 2003, 49 (4), pp.1031-41. ⟨10.1046/j.1365-2958.2003.03610.x⟩. ⟨hal-00013080⟩
  • Alain Blond, Michel Cheminant, Delphine Destoumieux-Garzón, Isabelle Ségalas-Milazzo, Jean Peduzzi, et al.. Thermolysin-linearized microcin J25 retains the structured core of the native macrocyclic peptide and displays antimicrobial activity.. European Journal of Biochemistry, 2002, 269 (24), pp.6212-22. ⟨hal-00013189⟩
  • Delphine Destoumieux-Garzón, Jean Peduzzi, Sylvie Rebuffat. Focus on modified microcins: structural features and mechanisms of action.. Biochimie, 2002, 84 (5-6), pp.511-9. ⟨hal-00013191⟩
  • A.Y. Lui, D. Destoumieux, A.V. Wong, C.H. Park, E.V. Valore, et al.. Human b-defensin-2 production in keratinocytes is regulated by interleukin 1, bacteria, and the state of differentiation. Journal of Investigative Dermatology, 2002, 118, pp.275-281. ⟨hal-00013591⟩
  • D. Destoumieux-Garzon, D. Saulnier, Josselin Garnier, C. Jouffrey, P. Bulet, et al.. Crustacean Immunity : Antifungal peptides are generated from the C terminus of shrimp hemocyanin in response to microbial challenge. Journal of Biological Chemistry, 2001, 276, pp.47070-47077. ⟨hal-00013599⟩

Communications dans un congrès57 documents

  • Delphine Destoumieux-Garzon. Antimicrobial peptides in the context of One Health. AMP 2022 7th International Symposium on Antimicrobial Peptides, Nov 2022, Paris, France. ⟨hal-03977226⟩
  • Noémie de San Nicolas, A. Asokan, R.D. Rosa, S.N. Voisin, Marie Agnès Travers, et al.. Functional DIversification of Big-Defensins and the shaping of oyster microbiota. AMP 2022 7th International Symposium on Antimicrobial Peptides, Nov 2022, Paris, France. ⟨hal-03976756⟩
  • D. Destoumieux-Garzon. invited speaker Session: ‘Antimicrobial peptides in the One Health Context & applications II’. AMP 2022 7th International Symposium on Antimicrobial Peptides, Nov 2022, Paris, France. ⟨hal-03976765⟩
  • Delphine Destoumieux-Garzon. Marine Invertebrates in a One Health Context. Séminaires de l'Université pontificale catholique de Valparaíso, Oct 2022, Valparaiso, Chile. ⟨hal-03977247⟩
  • Jeremie Vidal-Dupiol, Janan Gawra, Julien de Lorgeril, Yannick Gueguen, Fabrice Roux, et al.. Determinants and relative weight of genetic and epigenetic variation in the resistance of the oyster Crassostrea gigas to the Pacific Oyster Mortality Syndrome. EPIMAR 2022, Oct 2022, Woods Hole, Massachussets, United States. ⟨hal-03965076⟩
  • Noémie de San Nicolas, Raphael Rosa, C. Montagnani, Delphine Destoumieux-Garzon. Functional diversity of oyster big defensins (project DEPTH). KIM Sea & Coast 2022 Days, I-site MUSE, Sep 2022, Sète, France. ⟨hal-04007754⟩
  • Delphine Destoumieux-Garzon. Cooperation and cheating in a polymicrobial disease: the Pacific Oyster Mortality Syndrom. Ecological Immunology Workshop 2022 "Resistance, Tolerance & Symbionts", Sep 2022, Blossin, Germany. ⟨hal-03976803⟩
  • Daniel Oyanedel Trigo, Aurélie Mesnil, Jamal Saad, Jean Delmotte, Jean-Michel Escoubas, et al.. Marine invertebrates in a One Health context. Human and environmental drivers of diseases. ISME 18, CNRS INEE - International Symposium on Microbial Ecology, Aug 2022, Lausanne, Switzerland. ⟨hal-03991131⟩
  • Delphine Destoumieux-Garzon, Angela Sessitsch. Translational microbial ecology and One Health (Chairwoman). 18th International Symposium on Microbial Ecology, International Symposium on Microbial Ecology, Aug 2022, Lausanne (Suisse), Switzerland. ⟨hal-04007800⟩
  • Delphine Destoumieux-Garzon. Invertébrés marins et pathogènes émergents. Université d’été de la grande muraille verte. Prendre racine - Ecologie de la Santé, Université de Poitiers, Jul 2022, Poitiers, France. ⟨hal-03977268⟩
  • Daniel Oyanedel Trigo, Aurélie Mesnil, Jamal Saad, Jean Delmotte, Jean-Michel Escoubas, et al.. Influence humaine et environnementale sur l’émergence et la dynamique des pathogènes en milieu marin. InfectioTron – Journée d’animation du CNRS INEE, CNRS INEE, Jun 2022, Lyon, France. ⟨hal-03991115⟩
  • A. Asokan, Noémie de San Nicolas, H. Meudal, K. Loth, Delphine Destoumieux-Garzon, et al.. Enabling the synthesis of hydrophobic proteins using NCL-labile solubilizing tags: a case study of Crassostrea gigas big defensin 3. 22nd GFPP / BPGM5 French-Belgian Joint Meeting, Groupe Français des Peptides et Protéines, May 2022, Port Leucate, France. ⟨hal-03976595⟩
  • Delphine Destoumieux-Garzon, S. Netanyahu. Environmental drivers of pandemics: Research, Evidence and Prevention. HERA final conference, HERA Health and Environment Research Agenda, Mar 2022, Paris, France. ⟨hal-04007767⟩
  • Daniel Oyanedel Trigo, Arnaud Lagorce, Guillaume Charriere, Marie Agnès Travers, Delphine Destoumieux-Garzon. Immune-microbiota interplay in oyster health and disease. XXIst scientific meeting of the Italian Association of Developmental and Comparative Immunobiology (IADCI), Italian Association of Developmental and Comparative Immunobiology, Feb 2022, Padoue, Italy. ⟨hal-03991204⟩
  • Delphine Destoumieux-Garzon. L'apport des sciences de l’environnement, de l’évolution et de la socio-écologie face au risque futur de pandémies. Conférences Mensuelles de l'Académie Européenne Internationale des Sciences, Académie Européenne Internationale des Sciences, Feb 2022, Paris, France. ⟨hal-03977276⟩
  • Guillaume Mitta, Julien de Lorgeril, Aude Lucasson, Bruno Petton, Eve Toulza, et al.. Cracking the code of Pacific oyster mortality syndrom. Aqua 2018 14th International Symposium on Aquaculture Nutrition, Aug 2018, Montpellier, France. ⟨hal-03965691⟩
  • Julien de Lorgeril, Aude Lucasson, Bruno Petton, Eve Toulza, Philippe Haffner, et al.. An integrative approach to decipher the summer mortality syndrome affecting Pacific oysters. Immuninv 2017, Jun 2017, Lyon, France. ⟨hal-03966171⟩
  • Julien de Lorgeril, Aude Lucasson, Bruno Petton, Eve R Toulza, Philippe Haffner, et al.. An integrative approach to decipher the mortality syndrome affecting juvenile Pacific oysters. International Conference on Holobionts, Apr 2017, Paris, France. ⟨hal-03965715⟩
  • A.F. Delmas, V.P. Terrier, R.D. Rosa, A. Bressan, P. Marceau, et al.. Native Chemical ligation simplifies the access of multidomain antimicrobial peptides: application to the study of big-defensins. International symposium on AntiMicrobial Peptides (AMP2016), Jun 2016, Montpellier, France. ⟨hal-02892834⟩
  • Nour Essa, Mickael Chapelle, Pierre-Alain Girard, Jean-Luc Aymeric, Anne-Nathalie Volkoff, et al.. Cibles moléculaires chez Spodoptera frugiperda des facteurs de virulence des bactéries des genres Xenorhabdus et Photorhabdus. Immuninv 2014, May 2014, Dijon, France. ⟨hal-02154473⟩
  • Jeremie Vidal-Dupiol, Ophélie Ladrière, Nolwenn M. Dheilly, Delphine Destoumieux-Garzón, Sylvie Tambutté, et al.. The immune response of Pocillopora damicornis confronted to Vibrio coralliilyticus. 12th International Coral Reefs Symposium ICRS, Jul 2012, Cairns, Australia. pp.396. ⟨hal-03966000⟩
  • Jeremie Vidal-Dupiol, Ophélie Ladrière, Nolwenn M. Dheilly, Delphine Destoumieux-Garzón, Sylvie Tambutté, et al.. The immune response of Pocillopora damicornis confronted to Vibrio coralliilyticus. Immunologie des Invertébrés IMMUNINV 2012, 2012, Perpignan, France. pp.22. ⟨hal-03969008⟩
  • Jeremie Vidal-Dupiol, Ophélie Ladrière, Delphine Destoumieux-Garzón, P.E. Sautière, Anne-Leila Meistertzheim, et al.. Damicornin, the first AMP from a scleractinian coral: characterization and expression disturbance during vibriosis. Journées du Réseau Ecologie des Interactions Durables, Réseau Ecologie des Interactions Durables, 2012, Rennes, France. ⟨hal-03969025⟩
  • Vanessa W Petit, Alain Blond, Joelle Dupont, Jean Peduzzi, Christophe Goulard, et al.. Mechanism of action of litopenin PvHCt, a strictly antifungal peptide processed from hemocyanin in a penaeid shrimp. Second international symposium on antimicrobial peptides. Food, veterinary, medical and novel applications., Jun 2009, Saint Malo, France. ⟨hal-00394348⟩
  • Vanessa W Petit, Alain Blond, Chakib Djediat, Jean Peduzzi, Joelle Dupont, et al.. Three-dimensional structure and mechanism of action of an antifungal peptide generated from hemocyanin cleavage in a penaeid shrimp. 30th European Peptide Symposium, Aug 2008, Helsinski, Finland. ⟨hal-00294726⟩
  • Séverine Zirah, Kok-Phen Yan, Christophe Goulard, Sophie Duquesne, Delphine Destoumieux-Garzón, et al.. Lasso peptides. Bioactive peptides from Actinobacteria and Proteobacteria. Summer Schools in Applied Molecular Microbiology, Aug 2008, Dubrovnik, Croatia. ⟨hal-00393804⟩
  • G. Vassiliadis, J. Peduzzi, S. Zirah, D. Destoumieux-Garzón, S. Rebuffat. Les microcines-sidérophores, peptides antibactériens parasitant les voies d'import du fer. 34ème forrum Jeunes chercheurs. Explorer les systèmes biologiques : stratégies et innovation., Oct 2007, Ile des Embiez, France. ⟨hal-00187177⟩
  • G. Vassiliadis, J. Peduzzi, X. Thomas, S. Zirah, S. Rebuffat, et al.. Maturation of the antibacterial siderophore-peptide microcin E492. 6th International Gordon Research Conference on Antimicrobial Peptides, May 2007, Barga, Italy. ⟨hal-00147034⟩
  • S. Duquesne, D. Destoumieux-Garzón, S. Zirah, C. Goulard, J. Peduzzi, et al.. In vitro reconstitution of the biosynthesis of microcin J25, a lasso-type structured antimicrobial peptide. 6th International Gordon Research Conference on Antimicrobial Peptides, May 2007, Barga, Italy. ⟨hal-00147043⟩
  • S. Duquesne, D. Destoumieux-Garzón, S. Zirah, C. Goulard, J. Peduzzi, et al.. Reconstitution in vitro de la biosynthèse de la microcine J25, peptide antimicrobien structuré en lasso. 15ème réunion du Groupe Français des Peptides et Protéines, May 2007, Dinard, France. ⟨hal-00147045⟩
  • S. Duquesne, D. Destoumieux-Garzón, S. Zirah, T. A. Knappe, C. Goulard, et al.. Post-translational modification and folding of a lasso-type gene-encoded antimicrobial peptide require two enzymes only in Escherichia coli. Post-translational modification and folding of a lasso-type gene-encoded antimicrobial peptide require two enzymes only in Escherichia coli, 2007, Montréal, Canada. ⟨hal-00156048⟩
  • G. Vassiliadis, J. Peduzzi, D. Destoumieux-Garzón, S. Zirah, X. Thomas, et al.. Biosynthesis of siderophore-peptides, a class of potent antimicrobial peptides from enterobacteria, requires two precursors. Biosynthesis of siderophore-peptides, a class of potent antimicrobial peptides from enterobacteria, requires two precursors, 2007, Montréal, Canada. ⟨hal-00156045⟩
  • G. Vassiliadis, J. Peduzzi, D. Destoumieux-Garzón, S. Rebuffat. Microcin M, an antibacterial peptide from the probiotic bacterium Escherichia coli Nissle 1917. 1st International Symposium Food, Veterinary and Medical Applications of Antimicrobial Peptides, Jun 2006, ENITIAA, Nantes, France. ⟨hal-00146738⟩
  • G. Vassiliadis, J. Peduzzi, D. Destoumieux-Garzón, S. Rebuffat. Siderophore-microcins, antimicrobial peptides with potent activity against Enterobacteriaceae: structure, biosynthesis and recognition. 2nd International Congress Natural Peptides to Drugs, Apr 2006, Zermatt, Switzerland. ⟨hal-00146736⟩
  • D. Destoumieux-Garzón, J. Peduzzi, X. Thomas, C. Goulard, A. Blond, et al.. Parasitism of iron-siderophore receptors of Escherichia coli by the siderophore-peptide microcin E492m. 7th International symposium on microbial iron transport storage and metabolism, Jun 2005, Paris, France. ⟨hal-00013610⟩
  • S. Rebuffat, J. Peduzzi, X. Thomas, D. Destoumieux-Garzón, C. Goulard, et al.. Siderophore-peptide, a new type of antimicrobial peptide targetting iron-siderophore receptors at the outer membrane of Escherichia coli. 1st International Symposium on Biomolecules and Related Compounds, Mar 2005, Montpellier, France. ⟨hal-00147062⟩
  • D. Destoumieux-Garzón, X. Thomas, A. Blond, C. Afonso, N. Birlirakis, et al.. Microcin E492, a siderophore-mimicking antibacterial peptide that targets iron/siderophore receptors at the outer membrane of Escherichia coli. Vth Gordon Research Conference on Antimicrobial Peptides, Mar 2005, Ventura, United States. ⟨hal-00013608⟩
  • S. Duquesne, P. Boulanger, D. Destoumieux-Garzón, C. Goulard, L. Letellier, et al.. The iron-transporter FhuA is the receptor of the MccJ25 antimicrobial peptide at the bacterial membrane. The iron-transporter FhuA is the receptor of the MccJ25 antimicrobial peptide at the bacterial membrane, 2005, Prague, Czech Republic. pp.491-492. ⟨hal-00147248⟩
  • X. Thomas, D. Destoumieux-Garzón, A. Blond, J. Peduzzi, C. Afonso, et al.. Post-translationally modified microcin E492, a siderophore-peptide with potent antibacterial activity. Post-translationally modified microcin E492, a siderophore-peptide with potent antibacterial activity, 2005, Prague, Czech Republic. pp.156-157. ⟨hal-00147250⟩
  • X. Thomas, D. Destoumieux-Garzón, C. Afonso, A. Blond, J. Peduzzi, et al.. The post-translationally modified microcin E492 is a siderophore-peptide with potent antibacterial activity. Vth Workshop on Pore-Forming Toxins, Oct 2004, Mayence, Germany. ⟨hal-00013639⟩
  • X. Thomas, D. Destoumieux-Garzón, M. Santamaria, C. Goulard, Y. Bessin, et al.. Role of the catechol type siderophore receptors and inner-membrane protein TonB in microcin E492 antimicrobial activity against Escherichia coli. Vth Workshop on Pore-Forming Toxins, Oct 2004, Mayence, Germany. ⟨hal-00013642⟩
  • S. Duquesne, P. Boulanger, D. Destoumieux-Garzón, C. Goulard, L. Letellier, et al.. The iron-transporter FhuA is the receptor of the MccJ25 antibacterial peptide at the bacterial membrane. 3rd International and 28th European Peptide Symposium, Sep 2004, Prague, Czech Republic. ⟨hal-00013614⟩
  • X. Thomas, D. Destoumieux-Garzón, A. Blond, J. Peduzzi, C. Afonso, et al.. Post-translationally modified microcin E492, a siderophore-peptide with potent antibacterial activity. 3rd International and 28th European Peptide Symposium, Sep 2004, Prague, Czech Republic. ⟨hal-00013613⟩
  • X. Thomas, C. Afonso, D. Destoumieux-Garzón, J. Peduzzi, S. Rebuffat, et al.. Characterization of a posttranslational modification of Microcin E492 by ESI-ITMS. 52nd conference of the American Society for Mass Spectrometry (ASMS), May 2004, Nashville, Tennessee, United States. ⟨hal-00013612⟩
  • X. Thomas, D. Destoumieux-Garzón, C. Afonso, A. Blond, C. Goulard, et al.. Propriétés structurales et antimicrobiennes d'une forme modifiée de la microcine E492. 13ème réunion du groupe français des peptides et protéines, Oct 2003, Anglet-Biarritz, France. ⟨hal-00013625⟩
  • C. Afonso, X. Thomas, D. Destoumieux-Garzón, J.-P. Brouard, L. Dubost, et al.. Caractérisation d'une forme modifiée de la microcine E492 par ESI-ITMS. 20èmes Journées Françaises de Spectrométrie de Masse, Sep 2003, Toulouse, France. ⟨hal-00013620⟩
  • D. Destoumieux-Garzón, P. Boulanger, C. Goulard, A. Blond, M. Cheminant, et al.. The iron-transporter FhuA is the receptor of the macrocyclic antimicrobial peptide MccJ25 at the bacterial membrane. IVth Gordon Research Conference on Antimicrobial Peptides, Apr 2003, Il Ciocco, Italy. ⟨hal-00013616⟩
  • E. Bachère, D. Destoumieux-Garzón, M. Muñoz, F. Vandenbulcke, P. Bulet. Penaeidins, a family of antimicrobial peptides ubiquitous in Crustacea : involvement in shrimp immune response to infections. IVth Gordon Research Conference on Antimicrobial Peptides, 2003, Il Ciocco, Italy. ⟨hal-00013617⟩
  • D. Destoumieux-Garzón, P. Boulanger, C. Goulard, J. Peduzzi, L. Letellier, et al.. Etude du mode d'action de la microcine J25. Mise en évidence de l'interaction directe avec le récepteur membranaire FhuA. Congrès SFB-GEIMM, Sep 2002, Annecy, France. ⟨hal-00013633⟩
  • X. Thomas, D. Destoumieux-Garzón, C. Goulard, Y. Bessin, G. Molle, et al.. Structure et activité des formes modifiée et non modifiée de microcine E492. Congrès SFB-GEIMM, Sep 2002, Annecy, France. ⟨hal-00013636⟩
  • D. Destoumieux-Garzón, B. Boscher, X. Thomas, C. Goulard, M. Barthélémy, et al.. Structural features, antimicrobial and membrane properties of microcin E492. 27th European Peptide Symposium, Sep 2002, Sorrento, Italy. ⟨hal-00013626⟩
  • A. Blond, M. Cheminant, I. Ségalas-Milazzo, D. Destoumieux-Garzón, C. Goulard, et al.. Three-Dimensional structure of a thermolysin-linearized microcin J25: Evidence for an essential role of the 11-16 loop in microcin J25 structure and antimicrobial activity. 27th European Peptide Symposium, Sep 2002, Sorrento, Italy. ⟨hal-00013628⟩
  • A. Blond, M. Cheminant, D. Destoumieux-Garzón, C. Goulard, J. Peduzzi, et al.. Role de la boucle 11-16 dans le mécanisme d'action antibactérienne de la microcine J25. 12ème réunion du groupe français des peptides et protéines., Mar 2002, Aussois, France. ⟨hal-00013631⟩
  • A. Blond, M. Cheminant, I. Ségalas-Milazzo, D. Destoumieux-Garzón, C. Goulard, et al.. Three-Dimensional structure of a thermolysin-linearized microcin J25: Evidence for an essential role of the 11-16 loop in microcin J25 structure and antimicrobial activity. Peptides 2002, 2002, France. pp.866-867. ⟨hal-00013606⟩
  • D. Destoumieux-Garzón, B. Boscher, X. Thomas, C. Goulard, M. Barthélémy, et al.. Structural features, antimicrobial and membrane properties of Microcin E492. 2002, pp.462-463. ⟨hal-00013602⟩
  • D. Destoumieux. Protein studies, theorical aspects of purification and characterization HPLC and Mass Spectrometry. INCO-DC Workshop on Shrimp Immunity and Disease Control, an integrated approach, 2001, Hermosillo, Mexico. ⟨hal-00013645⟩
  • D. Destoumieux. Antimicrobial peptides from vertebrates and invertebrates. Structures and modes of action. INCO-DC Workshop on Shrimp Immunity and Disease Control, an integrated approach, 2001, Hemosillo, Mexico. ⟨hal-00013643⟩

Poster de conférence6 documents

  • Janan Gawra, J.B. Lamy, Mathilde Saccas, Julien de Lorgeril, Yannick Gueguen, et al.. Integrative approach of the resistance mechanisms to the mass mortality syndrome affecting the juvenile of the oyster Crassostrea gigas (POMS). First Epigenetic In Marine Biology Congress EPIMAR, Oct 2020, Montpellier ( Virtual Conference ), France. . ⟨hal-03969100⟩
  • A.F. Delmas, K. Loth, Herve Meudal, V.P. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02894301⟩
  • A. Delmas, K. Loth, Herve Meudal, V. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. NMR: a tool for Biology Xth, Jan 2017, Paris, France. ⟨hal-02453460⟩
  • Agnes Vergnes, Victor P. Terrier, Bressan Albert, Rafael Diego Rosa, Vincent Aucagne, et al.. Laligation native simplifie l’étude de l’activité etdu mécanismed’action des peptides antimicrobiens à multiples domaines :cas des Big défensines d’huître.. IIIèmes journées annuelles MuFoPAM « MultiFonction des Peptides AntiMicrobiens », Oct 2016, Tours, France. ⟨hal-02128427⟩
  • A.F. Delmas, V.P. Terrier, R.D. Rosa, A. Bressan, P. Marceau, et al.. Native Chemical ligation simplifies the access of multi-domain antimicrobial peptides: application to the study of big-defensins. 34th European Peptide Symposium 2016 (EPS2016), Sep 2016, Leipzig, Germany. ⟨hal-02895296⟩
  • Jeremie Vidal-Dupiol, Ophélie Ladrière, Anne-Leila Meistertzheim, Delphine Destoumieux-Garzon, Éric Tambutté, et al.. Antimicrobial response of the scleractinian coral Pocillopora damicornis to bacterial stress from Vibrio coralliilyticus. 11th European Coral Reefs Symposium, Dec 2010, Wageningen, Netherlands. ⟨hal-03969192⟩

Chapitres d'ouvrage1 document


Pré-publications, Documents de travail3 documents

  • Aude Lucasson, Xing Luo, Shogofa Mortaza, Julien de Lorgeril, Eve Toulza, et al.. A core of functionally complementary bacteria colonizes oysters in Pacific Oyster Mortality Syndrome. 2020. ⟨hal-03054359⟩
  • Delphine Destoumieux-Garzón, Pascal Bonnet, Céline Teplitsky, François Criscuolo, Pierre-Yves Henry, et al.. OneARK: Strengthening the links between animal production science and animal ecology. 2020. ⟨hal-02172445v3⟩
  • Etienne Robino, Aurore C. Poirier, Carmen Lopez-Joven, J.-C. Auguet, Tristan Rubio, et al.. Microbial predator-prey interactions could favor coincidental selection of diverse virulence factors in marine coastal waters. 2018. ⟨hal-03134835⟩

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