IHPE – CHARRIERE Guillaume

IHPE UMR 5244
Université de Montpellier
Place Eugène Bataillon CC 80
F-34095 Montpellier Cedex 5
Tel +33 (0)4-67-14-40-17
Fax +33(0)4-67-14-46-22
email: guillaume.charriere@umontpellier.fr

GRADE : Professeur des Universités, Université de Montpellier
EQUIPE : TREV
ENCADREMENT DE THESE :
ONILLON Laura (2020-2024)
MAROT Agathe (2024-2027)
RESPONSABILITES :
Co-responsable de l’équipe TREV
Membre du comité de pilotage du réseau REID « Réseau d’Etude des Interactions Durables »

RESEAUX SOCIAUX SCIENTIFIQUES:

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DOMAINE D’EXPERTISE-RECHERCHE :
Mes projets et activités de recherche se concentrent sur l’étude de la biologie cellulaire des interactions hôtes-pathogènes à l’interface entre l’immunologie et la microbiologie dans un contexte évolutif et écologique.
Je travaille depuis de nombreuses années sur la biologie cellulaire des phagocytes et l’immunité innée en interaction avec des bactéries pathogènes comme les Vibrios et sur des modèles multiples (allant des amibes libres aux invertébrés et vertébrés) avec un intérêt particulier pour l’immunologie comparée et l’évolution des mécanismes de virulence chez les bactéries pathogènes. Les approches développées sont interdisciplinaires et multi-échelles.
Actuellement je suis particulièrement intéressé par l’étude l’immunité cellulaire autonome ainsi que l’étude de la diversité des interactions amibes-vibrios dans l’environnement marin.

CURSUS :
2015 Habilitation à Diriger les Recherches HDR « La biologie des phagocytes au coeur des interactions hôtes-pathogènes, de Metchnikov à Van Valen »
2004 Doctorat (Université Paul Sabatier, Toulouse)

ENSEIGNEMENT :
– Responsable des enseignements en Immunologie et Hématologie au département Génie Biologique de l’IUT de Montpellier
– Interventions en Licence, Master 1 et Master 2 à l’université de Montpellier.

PUBLICATIONS :


40 documents

Articles dans une revue30 document

  • Caroline Montagnani, Benjamin Morga, Beatriz Novoa, Benjamin Gourbal, Amaro Saco, et al.. Trained immunity: Perspectives for disease control strategy in marine mollusc aquaculture. Reviews in Aquaculture, 2024, ⟨10.1111/raq.12906⟩. ⟨hal-04565659⟩
  • Delphine Destoumieux-Garzón, Caroline Montagnani, Luc Dantan, Noémie de San Nicolas, Marie-Agnès Travers, et al.. Cross-talk and mutual shaping between the immune system and the microbiota during an oyster's life. Philosophical Transactions of the Royal Society B: Biological Sciences, 2024, 379 (1901), ⟨10.1098/rstb.2023.0065⟩. ⟨hal-04515139⟩
  • Maurine Hammel, Fanny Touchard, E a V Burioli, Laure Paradis, Frédérique Cerqueira, et al.. Marine transmissible cancer navigates urbanised waters, threatening spillover. Proceedings of the Royal Society B: Biological Sciences, 2024, ⟨10.1098/rspb.2023.2541⟩. ⟨hal-04116826v2⟩
  • Erika A.V. Burioli, Maurine Hammel, Emmanuel Vignal, Jeremie Vidal-Dupiol, Guillaume Mitta, et al.. Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians. Open Biology, 2023, 13 (10), pp.230259. ⟨10.1098/rsob.230259⟩. ⟨hal-04245345⟩
  • Daniel Oyanedel, Arnaud Lagorce, Maxime Bruto, Philippe Haffner, Amandine Morot, et al.. Cooperation and cheating orchestrate Vibrio assemblages and polymicrobial synergy in oysters infected with OsHV-1 virus. Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (40), pp.e2305195120. ⟨10.1073/pnas.2305195120⟩. ⟨hal-04219877⟩
  • Noémie de San Nicolas, Aromal Asokan, Rafael D Rosa, Sébastien N Voisin, Marie-Agnès Travers, et al.. Functional Diversification of Oyster Big Defensins Generates Antimicrobial Specificity and Synergy against Members of the Microbiota. Marine drugs, 2022, 20 (12), pp.745. ⟨10.3390/md20120745⟩. ⟨hal-04246173⟩
  • Maurine Hammel, Alexis Simon, Christine Arbiol, Antonio Villalba, Erika A.V. Burioli, et al.. Prevalence and polymorphism of a mussel transmissible cancer in Europe. Molecular Ecology, 2022, 31 (3), pp.736-751. ⟨10.1111/mec.16052⟩. ⟨hal-03335752⟩
  • Erika A.V. Burioli, Maurine Hammel, Nicolas Bierne, Guillaume Charrière, Frédéric Thomas, et al.. Traits of a mussel transmissible cancer are reminiscent of a parasitic life style. Scientific Reports, 2021, 11 (1), pp.24110. ⟨10.1038/s41598-021-03598-w⟩. ⟨hal-03498948⟩
  • Daniel Oyanedel, Yannick Labreuche, Maxime Bruto, Hajar Amraoui, Etienne Robino, et al.. Vibrio splendidus O-antigen structure: A trade-off between virulence to oysters and resistance to grazers. Environmental Microbiology, 2020, 22, pp.4264 - 4278. ⟨10.1111/1462-2920.14996⟩. ⟨hal-02996139⟩
  • Delphine Destoumieux-Garzón, Laura Canesi, Daniel Oyanedel, Marie-Agnès Travers, Guillaume M Charrière, et al.. Vibrio-bivalve interactions in health and disease. Environmental Microbiology, 2020, Vibrios – from genes to ecosystems, 22 (10), pp.4323-4341. ⟨10.1111/1462-2920.15055⟩. ⟨hal-02915050⟩
  • Etienne Robino, Aurore Poirier, Hajar Amraoui, Sandra Le Bissonnais, Angélique Perret, et al.. Resistance of the oyster pathogen Vibrio tasmaniensis LGP32 against grazing by Vannella sp. marine amoeba involves Vsm and CopA virulence factors. Environmental Microbiology, 2019, 22, pp.4183 - 4197. ⟨10.1111/1462-2920.14770⟩. ⟨hal-02388995⟩
  • Tristan Rubio, Daniel Oyanedel, Yannick Labreuche, Eve Toulza, Xing Luo, et al.. Species-specific mechanisms of cytotoxicity toward immune cells determine the successful outcome of Vibrio infections. Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (28), pp.14238-14247. ⟨10.1073/pnas.1905747116⟩. ⟨hal-02163271⟩
  • Anaïs Portet, Silvain Pinaud, Cristian Chaparro, Richard Galinier, Nolwenn M. Dheilly, et al.. Sympatric versus allopatric evolutionary contexts shape differential immune response in Biomphalaria / Schistosoma interaction. PLoS Pathogens, 2019, 15 (3), pp.e1007647. ⟨10.1371/journal.ppat.1007647⟩. ⟨hal-02076267⟩
  • an Ngoc Nguyen, Elena Disconzi, Guillaume Charrière, Delphine Destoumieux-Garzón, Philippe Bouloc, et al.. csrB Gene Duplication Drives the Evolution of Redundant Regulatory Pathways Controlling Expression of the Major Toxic Secreted Metalloproteases in Vibrio tasmaniensis LGP32. MSphere, 2018, 3 (6), pp.e00582-18. ⟨10.1128/mSphere.00582-18⟩. ⟨hal-01945281⟩
  • Frédéric Thomas, Emmanuel Donnadieu, Guillaume Charriere, Camille Jacqueline, Aurélie Tasiemski, et al.. Is adaptive therapy natural?. PLoS Biology, 2018, 16 (10), pp.e2007066. ⟨10.1371/journal.pbio.2007066⟩. ⟨hal-01887358⟩
  • Camille Jacqueline, Nathalie Bonnefoy, Guillaume Charrière, Frédéric Thomas, Benjamin Roche. Personal history of infections and immunotherapy: Unexpected links and possible therapeutic opportunities. OncoImmunology, 2018, 7 (8), pp.e1466019. ⟨10.1080/2162402X.2018.1466019⟩. ⟨hal-01887524⟩
  • Julien de Lorgeril, Aude Lucasson, Bruno Petton, Eve Toulza, Caroline Montagnani, et al.. Immune-suppression by OsHV-1 viral infection causes fatal bacteraemia in Pacific oysters. Nature Communications, 2018, 9 (1), pp.4215. ⟨10.1038/s41467-018-06659-3⟩. ⟨hal-01898110⟩
  • A.S. Vanhove, T.P. Rubio, A.N. Nguyen, A. Lemire, D. Roche, et al.. Copper homeostasis at the host vibrio interface: lessons from intracellular vibrio transcriptomics. Environmental Microbiology, 2016, Pathogen Ecology, 18 (3), pp.875-888. ⟨10.1111/1462-2920.13083⟩. ⟨hal-01311061⟩
  • Audrey Sophie Vanhove, Marylise Duperthuy, Guillaume M Charrière, Frédérique Le Roux, David Goudenège, et al.. Outer membrane vesicles are vehicles for the delivery of Vibrio tasmaniensis virulence factors to oyster immune cells.. Environmental Microbiology, 2015, Pathogen ecology and lifestyles, 17 (4), pp.1152-1165. ⟨10.1111/1462-2920.12535⟩. ⟨halsde-01054322⟩
  • Nicolas Sisavath, Patrice Got, Guillaume Charrière, Delphine Destoumieux-Garzón, Hervé Cottet. Taking advantage of electric field induced bacterial aggregation for the study of interactions between bacteria and macromolecules by capillary electrophoresis. Analytical Chemistry, 2015, 87 (13), pp.6761-6768. ⟨10.1021/acs.analchem.5b00934⟩. ⟨hal-01259864⟩
  • Evelyne Bachère, Rafael Diego Rosa, Paulina Schmitt, Aurore Poirier, Nicolas Merou, et al.. The new insights into the oyster antimicrobial defense: cellular, molecular and genetic view. Fish and Shellfish Immunology, 2015, 46 (1), pp.50-64. ⟨10.1016/j.fsi.2015.02.040⟩. ⟨hal-01162911⟩
  • Anna Labernadie, Anais Bouissou, Patrick Delobelle, Stephanie Balor, Raphael Voituriez, et al.. Protrusion force microscopy reveals oscillatory force generation and mechanosensing activity of human macrophage podosomes. Nature Communications, 2014, 5 (1), 31p. ⟨10.1038/ncomms6343⟩. ⟨hal-01767580⟩
  • Aurore Poirier, Paulina Schmitt, Rafael Rosa, Audrey Vanhove, Sylvie Kieffer-Jaquinod, et al.. Antimicrobial Histones and DNA Traps in Invertebrate Immunity. Journal of Biological Chemistry, 2014, 289 (36), pp.24821-24831. ⟨10.1074/jbc.M114.576546⟩. ⟨hal-02086276⟩
  • Christel Vérollet, Guillaume Charriere, Arnaud Labrousse, Céline Cougoule, Véronique Le Cabec, et al.. Extracellular proteolysis in macrophage migration: Losing grip for a breakthrough. European Journal of Immunology, 2011, 41 (10), pp.2805-2813. ⟨10.1002/eji.201141538⟩. ⟨hal-02356055⟩
  • Hélène Botella, Pascale Peyron, Florence Levillain, Renaud Poincloux, Yannick Poquet, et al.. Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages.. Cell Host and Microbe, 2011, 10 (3), pp.248-59. ⟨10.1016/j.chom.2011.08.006⟩. ⟨hal-00674577⟩
  • Emeline van Goethem, Romain Guiet, Stephanie Balor, Guillaume Charriere, Renaud Poincloux, et al.. Macrophage podosomes go 3D. European Journal of Cell Biology, 2011, 90 (2-3), pp.224-236. ⟨10.1016/j.ejcb.2010.07.011⟩. ⟨hal-02356068⟩
  • Anna Labernadie, Christophe Thibault, Christophe Vieu, Isabelle Maridonneau-Parini, Guillaume Charriere. Dynamics of podosome stiffness revealed by atomic force microscopy. Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (49), pp.21016 - 21021. ⟨10.1073/pnas.1007835107⟩. ⟨hal-01767453⟩
  • Christel Vérollet, Yan Mei Zhang, Véronique Le Cabec, Julie Mazzolini, Guillaume Charriere, et al.. HIV-1 Nef Triggers Macrophage Fusion in a p61Hck- and Protease-Dependent Manner. Journal of Immunology, 2010, 184 (12), pp.7030-7039. ⟨10.4049/jimmunol.0903345⟩. ⟨hal-02356070⟩
  • Guillaume M Charrière, Béatrice Cousin, Emmanuelle Arnaud, Corinne Saillan-Barreau, Mireille André, et al.. Macrophage characteristics of stem cells revealed by transcriptome profiling.. Experimental Cell Research, 2006, 312 (17), pp.3205-14. ⟨10.1016/j.yexcr.2006.06.034⟩. ⟨hal-00319933⟩
  • Guillaume Charrière, Béatrice Cousin, Emmanuelle Arnaud, Mireille André, Francis Bacou, et al.. Preadipocyte conversion to macrophage. Evidence of plasticity. Journal of Biological Chemistry, 2003, 278 (11), pp.9850-9855. ⟨10.1074/jbc.M210811200⟩. ⟨hal-02678883⟩

Communications dans un congrès6 document

  • Noémie de San Nicolas, A. Asokan, R.D. Rosa, S.N. Voisin, Marie Agnès Travers, et al.. Functional DIversification of Big-Defensins and the shaping of oyster microbiota. AMP 2022 7th International Symposium on Antimicrobial Peptides, Nov 2022, Paris, France. ⟨hal-03976756⟩
  • Guillaume Charrière, M. Mandel. Investigating coincidental selection of virulence traits in Vibrios using an INseq approach (project VINSEQ). KIM Sea & Coast 2022 Days, I-site MUSE, Sep 2022, Sète, France. ⟨hal-04007741⟩
  • Daniel Oyanedel Trigo, Aurélie Mesnil, Jamal Saad, Jean Delmotte, Jean-Michel Escoubas, et al.. Marine invertebrates in a One Health context. Human and environmental drivers of diseases. ISME 18, CNRS INEE - International Symposium on Microbial Ecology, Aug 2022, Lausanne, Switzerland. ⟨hal-03991131⟩
  • Daniel Oyanedel Trigo, Aurélie Mesnil, Jamal Saad, Jean Delmotte, Jean-Michel Escoubas, et al.. Influence humaine et environnementale sur l’émergence et la dynamique des pathogènes en milieu marin. InfectioTron – Journée d’animation du CNRS INEE, CNRS INEE, Jun 2022, Lyon, France. ⟨hal-03991115⟩
  • Daniel Oyanedel Trigo, Arnaud Lagorce, Guillaume Charriere, Marie Agnès Travers, Delphine Destoumieux-Garzon. Immune-microbiota interplay in oyster health and disease. XXIst scientific meeting of the Italian Association of Developmental and Comparative Immunobiology (IADCI), Italian Association of Developmental and Comparative Immunobiology, Feb 2022, Padoue, Italy. ⟨hal-03991204⟩
  • Guillaume Mitta, Julien de Lorgeril, Aude Lucasson, Bruno Petton, Eve Toulza, et al.. Cracking the code of Pacific oyster mortality syndrom. Aqua 2018 14th International Symposium on Aquaculture Nutrition, Aug 2018, Montpellier, France. ⟨hal-03965691⟩

Chapitres d'ouvrage1 document


Pré-publications, Documents de travail3 document

  • Sébastien de la Forest Divonne, Juliette Pouzadoux, Océane Romatif, C. Montagnani, Guillaume Mitta, et al.. Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations. 2024. ⟨hal-04782332⟩
  • Jamal Saad, Viviane Boulo, David Goudenège, Coralie Broquard, Karl B Andree, et al.. Vibrio are a potential source of novel colistin-resistance genes in European coastal environments. 2024. ⟨hal-04782277⟩
  • Etienne Robino, Aurore C. Poirier, Carmen Lopez-Joven, J.-C. Auguet, Tristan Rubio, et al.. Microbial predator-prey interactions could favor coincidental selection of diverse virulence factors in marine coastal waters. 2018. ⟨hal-03134835⟩

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